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Facebook Twitter LinkedIn. The challenge for investors is that its lead XLMTM product has smaller commercial potential than other gene therapies, with fewer than babies born with it in the U. A risk with Regenxbio is the expiration of some patents on its vectors in the early s. Directory of sites. Drugmakers say building their own manufacturing plants is a response to rising costs and delays associated with relying on third-party contract manufacturers, which are also expanding to capitalize on demand. Google Firefox.